Maveral

• Antidepressants
• Anti-anxiety Agents
• Second-Generation
• Selective Serotonin Reuptake Inhibitors (SSRIs)
• ATC:N06AB08

• Dumirox
• Faverin
• Fevarin
• Floxyfral
• Fluvoxamina [Inn-Spanish]
• Fluvoxamine maleate
• Fluvoxaminum [Inn-Latin]
• Luvox
• Maveral

• No information avaliable

C₁₅H₂₁F₃N₂O₂

http://www.rxlist.com/cgi/generic/fluvox.htm

Maveral FDA

Maveral MSDS

Neth. pat. Appl. 7503310; H. B. A. Welle, V. Classen, U.S. pat. 4085225

318.335 g/mol

120-122.5 ^oC

No information avaliable

Solid

No information avaliable

Tablet

For treatment of depression and for Obsessive Compulsive Disorder (OCD)

Fluvoxamine is one of a class of antidepressants known as selective serotonin reuptake inhibitors (SSRIs). It is used to treat the depression associated with mood disorders. It is also used on occassion in the treatment of body dysmorphic disorder and anxiety. The antidepressant, antiobsessive-compulsive, and antibulimic actions of Fluvoxamine are presumed to be linked to its inhibition of CNS neuronal uptake of serotonin. In vitro studies show that Fluvoxamine is a potent and selective inhibitor of neuronal serotonin reuptake and has only very weak effects on norepinephrine and dopamine neuronal reuptake. Fluvoxamine has no significant affinity for adrenergic (alpha1, alpha2, beta), cholinergic, GABA, dopaminergic, histaminergic, serotonergic (5HT_1A, 5HT_1B, 5HT₂), or benzodiazepine receptors; antagonism of such receptors has been hypothesized to be associated with various anticholinergic, sedative, and cardiovascular effects for other psychotropic drugs. The chronic administration of Fluvoxamine was found to downregulate brain norepinephrine receptors, as has been observed with other drugs effective in the treatment of major depressive disorder. Fluvoxamine does not inhibit monoamine oxidase.

Well absorbed, bioavailability of fluvoxamine maleate is 53%.

Side effects include anorexia, constipation, dry mouth, headache, nausea, nervousness, skin rash, sleep problems, somnolence, liver toxicity, mania, increase urination, seizures, sweating increase, tremors, or Tourette's syndrome.

No information avaliable

Humans and other mammals