PharmacyCodes



Dumirox en es it fr

Dumirox Brand names, Dumirox Analogs

Dumirox Brand Names Mixture

  • No information avaliable

Dumirox Chemical_Formula

C15H21F3N2O2

Dumirox RX_link

http://www.rxlist.com/cgi/generic/fluvox.htm

Dumirox fda sheet

Dumirox FDA

Dumirox msds (material safety sheet)

Dumirox MSDS

Dumirox Synthesis Reference

Neth. pat. Appl. 7503310; H. B. A. Welle, V. Classen, U.S. pat. 4085225

Dumirox Molecular Weight

318.335 g/mol

Dumirox Melting Point

120-122.5 oC

Dumirox H2O Solubility

No information avaliable

Dumirox State

Solid

Dumirox LogP

No information avaliable

Dumirox Dosage Forms

Tablet

Dumirox Indication

For treatment of depression and for Obsessive Compulsive Disorder (OCD)

Dumirox Pharmacology

Fluvoxamine is one of a class of antidepressants known as selective serotonin reuptake inhibitors (SSRIs). It is used to treat the depression associated with mood disorders. It is also used on occassion in the treatment of body dysmorphic disorder and anxiety. The antidepressant, antiobsessive-compulsive, and antibulimic actions of Fluvoxamine are presumed to be linked to its inhibition of CNS neuronal uptake of serotonin. In vitro studies show that Fluvoxamine is a potent and selective inhibitor of neuronal serotonin reuptake and has only very weak effects on norepinephrine and dopamine neuronal reuptake. Fluvoxamine has no significant affinity for adrenergic (alpha1, alpha2, beta), cholinergic, GABA, dopaminergic, histaminergic, serotonergic (5HT1A, 5HT1B, 5HT2), or benzodiazepine receptors; antagonism of such receptors has been hypothesized to be associated with various anticholinergic, sedative, and cardiovascular effects for other psychotropic drugs. The chronic administration of Fluvoxamine was found to downregulate brain norepinephrine receptors, as has been observed with other drugs effective in the treatment of major depressive disorder. Fluvoxamine does not inhibit monoamine oxidase.

Dumirox Absorption

Well absorbed, bioavailability of fluvoxamine maleate is 53%.

Dumirox side effects and Toxicity

Side effects include anorexia, constipation, dry mouth, headache, nausea, nervousness, skin rash, sleep problems, somnolence, liver toxicity, mania, increase urination, seizures, sweating increase, tremors, or Tourette's syndrome.

Dumirox Patient Information

No information avaliable

Dumirox Organisms Affected

Humans and other mammals