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Fluvoxaminum [Inn-Latin] en es it fr

Fluvoxaminum [Inn-Latin] Brand names, Fluvoxaminum [Inn-Latin] Analogs

Fluvoxaminum [Inn-Latin] Brand Names Mixture

  • No information avaliable

Fluvoxaminum [Inn-Latin] Chemical_Formula

C15H21F3N2O2

Fluvoxaminum [Inn-Latin] RX_link

http://www.rxlist.com/cgi/generic/fluvox.htm

Fluvoxaminum [Inn-Latin] fda sheet

Fluvoxaminum_[Inn-Latin] FDA

Fluvoxaminum [Inn-Latin] msds (material safety sheet)

Fluvoxaminum_[Inn-Latin] MSDS

Fluvoxaminum [Inn-Latin] Synthesis Reference

Neth. pat. Appl. 7503310; H. B. A. Welle, V. Classen, U.S. pat. 4085225

Fluvoxaminum [Inn-Latin] Molecular Weight

318.335 g/mol

Fluvoxaminum [Inn-Latin] Melting Point

120-122.5 oC

Fluvoxaminum [Inn-Latin] H2O Solubility

No information avaliable

Fluvoxaminum [Inn-Latin] State

Solid

Fluvoxaminum [Inn-Latin] LogP

No information avaliable

Fluvoxaminum [Inn-Latin] Dosage Forms

Tablet

Fluvoxaminum [Inn-Latin] Indication

For treatment of depression and for Obsessive Compulsive Disorder (OCD)

Fluvoxaminum [Inn-Latin] Pharmacology

Fluvoxamine is one of a class of antidepressants known as selective serotonin reuptake inhibitors (SSRIs). It is used to treat the depression associated with mood disorders. It is also used on occassion in the treatment of body dysmorphic disorder and anxiety. The antidepressant, antiobsessive-compulsive, and antibulimic actions of Fluvoxamine are presumed to be linked to its inhibition of CNS neuronal uptake of serotonin. In vitro studies show that Fluvoxamine is a potent and selective inhibitor of neuronal serotonin reuptake and has only very weak effects on norepinephrine and dopamine neuronal reuptake. Fluvoxamine has no significant affinity for adrenergic (alpha1, alpha2, beta), cholinergic, GABA, dopaminergic, histaminergic, serotonergic (5HT1A, 5HT1B, 5HT2), or benzodiazepine receptors; antagonism of such receptors has been hypothesized to be associated with various anticholinergic, sedative, and cardiovascular effects for other psychotropic drugs. The chronic administration of Fluvoxamine was found to downregulate brain norepinephrine receptors, as has been observed with other drugs effective in the treatment of major depressive disorder. Fluvoxamine does not inhibit monoamine oxidase.

Fluvoxaminum [Inn-Latin] Absorption

Well absorbed, bioavailability of fluvoxamine maleate is 53%.

Fluvoxaminum [Inn-Latin] side effects and Toxicity

Side effects include anorexia, constipation, dry mouth, headache, nausea, nervousness, skin rash, sleep problems, somnolence, liver toxicity, mania, increase urination, seizures, sweating increase, tremors, or Tourette's syndrome.

Fluvoxaminum [Inn-Latin] Patient Information

No information avaliable

Fluvoxaminum [Inn-Latin] Organisms Affected

Humans and other mammals