Fluvoxamine maleate en es it fr

Fluvoxamine maleate Brand names, Fluvoxamine maleate Analogs

Fluvoxamine maleate Brand Names Mixture

  • No information avaliable

Fluvoxamine maleate Chemical_Formula


Fluvoxamine maleate RX_link


Fluvoxamine maleate fda sheet

Fluvoxamine_maleate FDA

Fluvoxamine maleate msds (material safety sheet)

Fluvoxamine_maleate MSDS

Fluvoxamine maleate Synthesis Reference

Neth. pat. Appl. 7503310; H. B. A. Welle, V. Classen, U.S. pat. 4085225

Fluvoxamine maleate Molecular Weight

318.335 g/mol

Fluvoxamine maleate Melting Point

120-122.5 oC

Fluvoxamine maleate H2O Solubility

No information avaliable

Fluvoxamine maleate State


Fluvoxamine maleate LogP

No information avaliable

Fluvoxamine maleate Dosage Forms


Fluvoxamine maleate Indication

For treatment of depression and for Obsessive Compulsive Disorder (OCD)

Fluvoxamine maleate Pharmacology

Fluvoxamine is one of a class of antidepressants known as selective serotonin reuptake inhibitors (SSRIs). It is used to treat the depression associated with mood disorders. It is also used on occassion in the treatment of body dysmorphic disorder and anxiety. The antidepressant, antiobsessive-compulsive, and antibulimic actions of Fluvoxamine are presumed to be linked to its inhibition of CNS neuronal uptake of serotonin. In vitro studies show that Fluvoxamine is a potent and selective inhibitor of neuronal serotonin reuptake and has only very weak effects on norepinephrine and dopamine neuronal reuptake. Fluvoxamine has no significant affinity for adrenergic (alpha1, alpha2, beta), cholinergic, GABA, dopaminergic, histaminergic, serotonergic (5HT1A, 5HT1B, 5HT2), or benzodiazepine receptors; antagonism of such receptors has been hypothesized to be associated with various anticholinergic, sedative, and cardiovascular effects for other psychotropic drugs. The chronic administration of Fluvoxamine was found to downregulate brain norepinephrine receptors, as has been observed with other drugs effective in the treatment of major depressive disorder. Fluvoxamine does not inhibit monoamine oxidase.

Fluvoxamine maleate Absorption

Well absorbed, bioavailability of fluvoxamine maleate is 53%.

Fluvoxamine maleate side effects and Toxicity

Side effects include anorexia, constipation, dry mouth, headache, nausea, nervousness, skin rash, sleep problems, somnolence, liver toxicity, mania, increase urination, seizures, sweating increase, tremors, or Tourette's syndrome.

Fluvoxamine maleate Patient Information

No information avaliable

Fluvoxamine maleate Organisms Affected

Humans and other mammals