Lycoremin
Brand names,
Lycoremin
Analogs
Lycoremin
Brand Names Mixture
Lycoremin
Chemical_Formula
C17H21NO3
Lycoremin
RX_link
http://www.rxlist.com/cgi/generic/reminyl.htm
Lycoremin
fda sheet
Lycoremin
msds (material safety sheet)
Lycoremin
Synthesis Reference
Czollner, L. et al. ARKIVOC 191-200 (2001).
Lycoremin
Molecular Weight
287.354 g/mol
Lycoremin
Melting Point
269-270 oC (HBr salt)
Lycoremin
H2O Solubility
10 mg/mL (HBr salt)
Lycoremin
State
Solid
Lycoremin
LogP
2.369
Lycoremin
Dosage Forms
Capsules (extended-release)
Lycoremin
Indication
For the treatment of mild to moderate dementia of the Alzheimer's type.
Lycoremin
Pharmacology
Galantamine is a parasympathomimetic, specifically, a reversible cholinesterase inhibitor. Galantamine is indicated for the treatment of mild to moderate dementia of the Alzheimer's type. Galantamine is postulated to exert its therapeutic effect by enhancing cholinergic function. This is accomplished by increasing the concentration of acetylcholine through reversible inhibition of its hydrolysis by acetylcholinesterase. If this proposed mechanism of action is correct, Galantamine's effect may lessen as the disease process advances and fewer cholinergic neurons remain functionally intact. There is no evidence that Galantamine alters the course of the underlying dementing process.
Lycoremin
Absorption
No information avaliable
Lycoremin
side effects and Toxicity
LD50=75 mg/kg (rat)
Lycoremin
Patient Information
Galantamine is used to treat the symptoms of Alzheimer's disease (AD; a brain disease that slowly destroys the
memory and the ability to think, learn, communicate and handle daily activities). Galantamine is in a class of
medications called acetylcholinesterase inhibitors. It works by increasing the amount of a certain natural substance
in the brain that is needed for memory and thought. Galantamine may improve the ability to think and remember or slow
the loss of these abilities in people who have AD. However, galantamine will not cure AD or prevent the loss of
mental abilities at some time in the future.
Lycoremin
Organisms Affected
Humans and other mammals