Jilkon
Jilkon Brand names, Jilkon Analogs
Jilkon Brand Names Mixture
- No information avaliable
Jilkon Chemical_Formula
C17H21NO3
Jilkon RX_link
http://www.rxlist.com/cgi/generic/reminyl.htm
Jilkon fda sheet
Jilkon msds (material safety sheet)
Jilkon Synthesis Reference
Czollner, L. et al. ARKIVOC 191-200 (2001).
Jilkon Molecular Weight
287.354 g/mol
Jilkon Melting Point
269-270 oC (HBr salt)
Jilkon H2O Solubility
10 mg/mL (HBr salt)
Jilkon State
Solid
Jilkon LogP
2.369
Jilkon Dosage Forms
Capsules (extended-release)
Jilkon Indication
For the treatment of mild to moderate dementia of the Alzheimer's type.
Jilkon Pharmacology
Galantamine is a parasympathomimetic, specifically, a reversible cholinesterase inhibitor. Galantamine is indicated for the treatment of mild to moderate dementia of the Alzheimer's type. Galantamine is postulated to exert its therapeutic effect by enhancing cholinergic function. This is accomplished by increasing the concentration of acetylcholine through reversible inhibition of its hydrolysis by acetylcholinesterase. If this proposed mechanism of action is correct, Galantamine's effect may lessen as the disease process advances and fewer cholinergic neurons remain functionally intact. There is no evidence that Galantamine alters the course of the underlying dementing process.
Jilkon Absorption
No information avaliable
Jilkon side effects and Toxicity
LD50=75 mg/kg (rat)
Jilkon Patient Information
Galantamine is used to treat the symptoms of Alzheimer's disease (AD; a brain disease that slowly destroys the memory and the ability to think, learn, communicate and handle daily activities). Galantamine is in a class of medications called acetylcholinesterase inhibitors. It works by increasing the amount of a certain natural substance in the brain that is needed for memory and thought. Galantamine may improve the ability to think and remember or slow the loss of these abilities in people who have AD. However, galantamine will not cure AD or prevent the loss of mental abilities at some time in the future.
Jilkon Organisms Affected
Humans and other mammals
