Galanthamine hydrobromide
Galanthamine hydrobromide Brand names, Galanthamine hydrobromide Analogs
Galanthamine hydrobromide Brand Names Mixture
- No information avaliable
Galanthamine hydrobromide Chemical_Formula
C17H21NO3
Galanthamine hydrobromide RX_link
http://www.rxlist.com/cgi/generic/reminyl.htm
Galanthamine hydrobromide fda sheet
Galanthamine hydrobromide msds (material safety sheet)
Galanthamine hydrobromide Synthesis Reference
Czollner, L. et al. ARKIVOC 191-200 (2001).
Galanthamine hydrobromide Molecular Weight
287.354 g/mol
Galanthamine hydrobromide Melting Point
269-270 oC (HBr salt)
Galanthamine hydrobromide H2O Solubility
10 mg/mL (HBr salt)
Galanthamine hydrobromide State
Solid
Galanthamine hydrobromide LogP
2.369
Galanthamine hydrobromide Dosage Forms
Capsules (extended-release)
Galanthamine hydrobromide Indication
For the treatment of mild to moderate dementia of the Alzheimer's type.
Galanthamine hydrobromide Pharmacology
Galantamine is a parasympathomimetic, specifically, a reversible cholinesterase inhibitor. Galantamine is indicated for the treatment of mild to moderate dementia of the Alzheimer's type. Galantamine is postulated to exert its therapeutic effect by enhancing cholinergic function. This is accomplished by increasing the concentration of acetylcholine through reversible inhibition of its hydrolysis by acetylcholinesterase. If this proposed mechanism of action is correct, Galantamine's effect may lessen as the disease process advances and fewer cholinergic neurons remain functionally intact. There is no evidence that Galantamine alters the course of the underlying dementing process.
Galanthamine hydrobromide Absorption
No information avaliable
Galanthamine hydrobromide side effects and Toxicity
LD50=75 mg/kg (rat)
Galanthamine hydrobromide Patient Information
Galantamine is used to treat the symptoms of Alzheimer's disease (AD; a brain disease that slowly destroys the memory and the ability to think, learn, communicate and handle daily activities). Galantamine is in a class of medications called acetylcholinesterase inhibitors. It works by increasing the amount of a certain natural substance in the brain that is needed for memory and thought. Galantamine may improve the ability to think and remember or slow the loss of these abilities in people who have AD. However, galantamine will not cure AD or prevent the loss of mental abilities at some time in the future.
Galanthamine hydrobromide Organisms Affected
Humans and other mammals
