Luprac

Luprac Brand names, Luprac Analogs

Luprac Brand Names Mixture

No information avaliable

Luprac Chemical_Formula

C₁₆H₂₀N₄O₃S

Luprac RX_link

http://www.rxlist.com/cgi/generic/demadex.htm

Luprac fda sheet

Luprac msds (material safety sheet)

Luprac MSDS

Luprac Synthesis Reference

No information avaliable

Luprac Molecular Weight

348.421 g/mol

Luprac Melting Point

163-164 ^oC (decomposition)

Luprac H₂O Solubility

Soluble

Luprac State

Solid

Luprac LogP

2.404

Luprac Dosage Forms

Liquid; Tablet

Luprac Indication

For the treatment of hypertension, edema induced by congestive heart failure or renal disease, and ascites associated with hepatic disease.

Luprac Pharmacology

Torasemide, a monosulfonamyl loop diuretic, differs form other thiazide diuretics in that a double ring system is incorporated into its structure. Torasemide is used alone or with atenolol in the management of hypertension and edema. Micropuncture studies in animals have shown that torsemide acts from within the lumen of the thick ascending portion of the loop of Henle, where it inhibits the Na⁺/K⁺/2Cl^--carrier system.

Luprac Absorption

Bioavailability is approximately 80%. Serum concentration peaks after approximately 1 hour.

Luprac side effects and Toxicity

LD₅₀ = 5 g/kg (rat, oral), 500 mg/kg (rat, intravenous). Side effects include dizziness, headache, nausea and vomiting.

Luprac Patient Information