Torsemide (USP)

Torsemide (USP) Brand names, Torsemide (USP) Analogs

Torsemide (USP) Brand Names Mixture

No information avaliable

Torsemide (USP) Chemical_Formula

C₁₆H₂₀N₄O₃S

Torsemide (USP) RX_link

http://www.rxlist.com/cgi/generic/demadex.htm

Torsemide (USP) fda sheet

Torsemide (USP) msds (material safety sheet)

Torsemide_(USP) MSDS

Torsemide (USP) Synthesis Reference

No information avaliable

Torsemide (USP) Molecular Weight

348.421 g/mol

Torsemide (USP) Melting Point

163-164 ^oC (decomposition)

Torsemide (USP) H₂O Solubility

Soluble

Torsemide (USP) State

Solid

Torsemide (USP) LogP

2.404

Torsemide (USP) Dosage Forms

Liquid; Tablet

Torsemide (USP) Indication

For the treatment of hypertension, edema induced by congestive heart failure or renal disease, and ascites associated with hepatic disease.

Torsemide (USP) Pharmacology

Torasemide, a monosulfonamyl loop diuretic, differs form other thiazide diuretics in that a double ring system is incorporated into its structure. Torasemide is used alone or with atenolol in the management of hypertension and edema. Micropuncture studies in animals have shown that torsemide acts from within the lumen of the thick ascending portion of the loop of Henle, where it inhibits the Na⁺/K⁺/2Cl^--carrier system.

Torsemide (USP) Absorption

Bioavailability is approximately 80%. Serum concentration peaks after approximately 1 hour.

Torsemide (USP) side effects and Toxicity

LD₅₀ = 5 g/kg (rat, oral), 500 mg/kg (rat, intravenous). Side effects include dizziness, headache, nausea and vomiting.

Torsemide (USP) Patient Information