L-Histidine (JAN/USP) en es it fr

L-Histidine (JAN/USP) Brand names, L-Histidine (JAN/USP) Analogs

L-Histidine (JAN/USP) Brand Names Mixture

  • No information avaliable

L-Histidine (JAN/USP) Chemical_Formula

C6H9N3O2

L-Histidine (JAN/USP) RX_link

No information avaliable

L-Histidine (JAN/USP) fda sheet

L-Histidine (JAN/USP) msds (material safety sheet)

http://physchem.ox.ac.uk/MSDS/HI/l-histidine.html

L-Histidine (JAN/USP) Synthesis Reference

No information avaliable

L-Histidine (JAN/USP) Molecular Weight

155.15 g/mol

L-Histidine (JAN/USP) Melting Point

282 oC

L-Histidine (JAN/USP) H2O Solubility

No information avaliable

L-Histidine (JAN/USP) State

Solid, white crystals

L-Histidine (JAN/USP) LogP

-3.461

L-Histidine (JAN/USP) Dosage Forms

Capsules, powder and tablets

L-Histidine (JAN/USP) Indication

The actions of supplemental L-histidine are entirely unclear. It may have some immunomodulatory as well as antioxidant activity. L-histidine may be indicated for use in some with rheumatoid arthritis. It is not indicated for treatment of anemia or uremia or for lowering serum cholesterol.

L-Histidine (JAN/USP) Pharmacology

Is found abundantly in hemoglobin; has been used in the treatment of rheumatoid arthritis, allergic diseases, ulcers & anemia. A deficiency can cause poor hearing.

L-Histidine (JAN/USP) Absorption

Absorbed from the small intestine via an active transport mechanism requiring the presence of sodium.

L-Histidine (JAN/USP) side effects and Toxicity

ORL-RAT LD50 > 15000 mg kg-1, IPR-RAT LD50 > 8000 mg kg-1, ORL-MUS LD50 > 15000 mg kg-1, IVN-MUS LD50 > 2000 mg kg-1; Mild gastrointestinal side effects.

L-Histidine (JAN/USP) Patient Information

L-histidine supplements should be avoided by children, pregnant women and nursing mothers. Those with allergies or peptic ulcer disease should only use L-histidine supplements under strict medical supervision. Although there are no reports of adverse events in these groups, increased histamine production from L-histidine might negatively affect those with these conditions.

L-Histidine (JAN/USP) Organisms Affected

Humans and other mammals