L-Alanine, 3-(1H-imidazol-4-yl)-
Brand names,
L-Alanine, 3-(1H-imidazol-4-yl)-
Analogs
L-Alanine, 3-(1H-imidazol-4-yl)-
Brand Names Mixture
L-Alanine, 3-(1H-imidazol-4-yl)-
Chemical_Formula
C6H9N3O2
L-Alanine, 3-(1H-imidazol-4-yl)-
RX_link
No information avaliable
L-Alanine, 3-(1H-imidazol-4-yl)-
fda sheet
L-Alanine, 3-(1H-imidazol-4-yl)-
msds (material safety sheet)
L-Alanine, 3-(1H-imidazol-4-yl)-
Synthesis Reference
No information avaliable
L-Alanine, 3-(1H-imidazol-4-yl)-
Molecular Weight
155.15 g/mol
L-Alanine, 3-(1H-imidazol-4-yl)-
Melting Point
282 oC
L-Alanine, 3-(1H-imidazol-4-yl)-
H2O Solubility
No information avaliable
L-Alanine, 3-(1H-imidazol-4-yl)-
State
Solid, white crystals
L-Alanine, 3-(1H-imidazol-4-yl)-
LogP
-3.461
L-Alanine, 3-(1H-imidazol-4-yl)-
Dosage Forms
Capsules, powder and tablets
L-Alanine, 3-(1H-imidazol-4-yl)-
Indication
The actions of supplemental L-histidine are entirely unclear. It may have some immunomodulatory as well as antioxidant activity. L-histidine may be indicated for use in some with rheumatoid arthritis. It is not indicated for treatment of anemia or uremia or for lowering serum cholesterol.
L-Alanine, 3-(1H-imidazol-4-yl)-
Pharmacology
Is found abundantly in hemoglobin; has been used in the treatment of rheumatoid arthritis, allergic diseases, ulcers & anemia. A deficiency can cause poor hearing.
L-Alanine, 3-(1H-imidazol-4-yl)-
Absorption
Absorbed from the small intestine via an active transport mechanism requiring the presence of sodium.
L-Alanine, 3-(1H-imidazol-4-yl)-
side effects and Toxicity
ORL-RAT LD50 > 15000 mg kg-1, IPR-RAT LD50 > 8000 mg kg-1, ORL-MUS LD50 > 15000 mg kg-1, IVN-MUS LD50 > 2000 mg kg-1; Mild gastrointestinal side effects.
L-Alanine, 3-(1H-imidazol-4-yl)-
Patient Information
L-histidine supplements should be avoided by children, pregnant women and nursing mothers. Those with allergies or peptic ulcer disease should only use L-histidine supplements under strict medical supervision. Although there are no reports of adverse events in these groups, increased histamine production from L-histidine might negatively affect those with these conditions.
L-Alanine, 3-(1H-imidazol-4-yl)-
Organisms Affected
Humans and other mammals