Ketotifene fumarate
Ketotifene fumarate Brand names, Ketotifene fumarate Analogs
Ketotifene fumarate Brand Names Mixture
- No information avaliable
Ketotifene fumarate Chemical_Formula
C11H12N2S
Ketotifene fumarate RX_link
http://www.rxlist.com/cgi/generic3/levamisole.htm
Ketotifene fumarate fda sheet
Ketotifene fumarate msds (material safety sheet)
Ketotifene fumarate Synthesis Reference
No information avaliable
Ketotifene fumarate Molecular Weight
204.292 g/mol
Ketotifene fumarate Melting Point
264-265 oC
Ketotifene fumarate H2O Solubility
210 mg/mL
Ketotifene fumarate State
Solid
Ketotifene fumarate LogP
2.046
Ketotifene fumarate Dosage Forms
Tablet
Ketotifene fumarate Indication
For adjuvant treatment in combination with fluorouracil after surgical resection in patients with Dukes' stage C colon cancer. Also used to treat malignant melanoma and head/neck cancer.
Ketotifene fumarate Pharmacology
Levamisole is a synthetic imidazothiazole derivative that has been widely used in treatment of worm infestations in both humans and animals. As an anthelmintic, it probably works by targeting the nematode nicotinergic acetylcholine receptor. As an immunomodulator, it appears that Levamisole is an immunostimulant which has been shown to increase NK cells and activated T-cells in patients receiving this adjuvantly along with 5FU for Stage III colon cancer.
Ketotifene fumarate Absorption
Levamisole is rapidly absorbed (2 hours) from the gastrointestinal tract.
Ketotifene fumarate side effects and Toxicity
LD50 = 40 mg/kg (Pigs, subcutaneous); LD50 = 180 mg/kg (rat, oral)
Ketotifene fumarate Patient Information
http://www.drugs.com/MTM/letrozole.html
Ketotifene fumarate Organisms Affected
Humans and other mammals
