Zaditor
Zaditor Brand names, Zaditor Analogs
Zaditor Brand Names Mixture
- No information avaliable
Zaditor Chemical_Formula
C11H12N2S
Zaditor RX_link
http://www.rxlist.com/cgi/generic3/levamisole.htm
Zaditor fda sheet
Zaditor msds (material safety sheet)
Zaditor Synthesis Reference
No information avaliable
Zaditor Molecular Weight
204.292 g/mol
Zaditor Melting Point
264-265 oC
Zaditor H2O Solubility
210 mg/mL
Zaditor State
Solid
Zaditor LogP
2.046
Zaditor Dosage Forms
Tablet
Zaditor Indication
For adjuvant treatment in combination with fluorouracil after surgical resection in patients with Dukes' stage C colon cancer. Also used to treat malignant melanoma and head/neck cancer.
Zaditor Pharmacology
Levamisole is a synthetic imidazothiazole derivative that has been widely used in treatment of worm infestations in both humans and animals. As an anthelmintic, it probably works by targeting the nematode nicotinergic acetylcholine receptor. As an immunomodulator, it appears that Levamisole is an immunostimulant which has been shown to increase NK cells and activated T-cells in patients receiving this adjuvantly along with 5FU for Stage III colon cancer.
Zaditor Absorption
Levamisole is rapidly absorbed (2 hours) from the gastrointestinal tract.
Zaditor side effects and Toxicity
LD50 = 40 mg/kg (Pigs, subcutaneous); LD50 = 180 mg/kg (rat, oral)
Zaditor Patient Information
http://www.drugs.com/MTM/letrozole.html
Zaditor Organisms Affected
Humans and other mammals
