Ketotifene [INN-French] en es it fr

Ketotifene [INN-French] Brand names, Ketotifene [INN-French] Analogs

Ketotifene [INN-French] Brand Names Mixture

  • No information avaliable

Ketotifene [INN-French] Chemical_Formula


Ketotifene [INN-French] RX_link

Ketotifene [INN-French] fda sheet

Ketotifene_[INN-French] FDA

Ketotifene [INN-French] msds (material safety sheet)

Ketotifene_[INN-French] MSDS

Ketotifene [INN-French] Synthesis Reference

No information avaliable

Ketotifene [INN-French] Molecular Weight

204.292 g/mol

Ketotifene [INN-French] Melting Point

264-265 oC

Ketotifene [INN-French] H2O Solubility

210 mg/mL

Ketotifene [INN-French] State


Ketotifene [INN-French] LogP


Ketotifene [INN-French] Dosage Forms


Ketotifene [INN-French] Indication

For adjuvant treatment in combination with fluorouracil after surgical resection in patients with Dukes' stage C colon cancer. Also used to treat malignant melanoma and head/neck cancer.

Ketotifene [INN-French] Pharmacology

Levamisole is a synthetic imidazothiazole derivative that has been widely used in treatment of worm infestations in both humans and animals. As an anthelmintic, it probably works by targeting the nematode nicotinergic acetylcholine receptor. As an immunomodulator, it appears that Levamisole is an immunostimulant which has been shown to increase NK cells and activated T-cells in patients receiving this adjuvantly along with 5FU for Stage III colon cancer.

Ketotifene [INN-French] Absorption

Levamisole is rapidly absorbed (2 hours) from the gastrointestinal tract.

Ketotifene [INN-French] side effects and Toxicity

LD50 = 40 mg/kg (Pigs, subcutaneous); LD50 = 180 mg/kg (rat, oral)

Ketotifene [INN-French] Patient Information

Ketotifene [INN-French] Organisms Affected

Humans and other mammals