Ketotifen
Ketotifen Brand names, Ketotifen Analogs
Ketotifen Brand Names Mixture
- No information avaliable
Ketotifen Chemical_Formula
C11H12N2S
Ketotifen RX_link
http://www.rxlist.com/cgi/generic3/levamisole.htm
Ketotifen fda sheet
Ketotifen msds (material safety sheet)
Ketotifen Synthesis Reference
No information avaliable
Ketotifen Molecular Weight
204.292 g/mol
Ketotifen Melting Point
264-265 oC
Ketotifen H2O Solubility
210 mg/mL
Ketotifen State
Solid
Ketotifen LogP
2.046
Ketotifen Dosage Forms
Tablet
Ketotifen Indication
For adjuvant treatment in combination with fluorouracil after surgical resection in patients with Dukes' stage C colon cancer. Also used to treat malignant melanoma and head/neck cancer.
Ketotifen Pharmacology
Levamisole is a synthetic imidazothiazole derivative that has been widely used in treatment of worm infestations in both humans and animals. As an anthelmintic, it probably works by targeting the nematode nicotinergic acetylcholine receptor. As an immunomodulator, it appears that Levamisole is an immunostimulant which has been shown to increase NK cells and activated T-cells in patients receiving this adjuvantly along with 5FU for Stage III colon cancer.
Ketotifen Absorption
Levamisole is rapidly absorbed (2 hours) from the gastrointestinal tract.
Ketotifen side effects and Toxicity
LD50 = 40 mg/kg (Pigs, subcutaneous); LD50 = 180 mg/kg (rat, oral)
Ketotifen Patient Information
http://www.drugs.com/MTM/letrozole.html
Ketotifen Organisms Affected
Humans and other mammals
