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Brand names,
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Analogs
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Brand Names Mixture
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Chemical_Formula
C19H16ClNO4
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RX_link
http://www.rxlist.com/cgi/generic/indometh.htm
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fda sheet
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msds (material safety sheet)
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Synthesis Reference
No information avaliable
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Molecular Weight
357.787 g/mol
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Melting Point
158 oC
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H2O Solubility
0.937 mg/L
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State
Solid
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LogP
3.655
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Dosage Forms
Capsule
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Indication
For moderate to severe rheumatoid arthritis including acute flares of chronic disease, ankylosing spondylitis, osteoarthritis, acute painful shoulder (bursitis and/or tendinitis) and acute gouty arthritis.
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Pharmacology
Indomethacin, a nonsteroidal antiinflammatory drug (NSAID) with analgesic and antipyretic properties, is used to treat osteoarthritis and control acute pain.
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Absorption
No information avaliable
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side effects and Toxicity
No information avaliable
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Patient Information
Indomethacin, like other drugs of its class, is not free of side effects. The side effects of these drugs can
cause discomfort and rarely, there are more serious side effects, such as gastrointestinal bleeding, which may result
in hospitalization and even fatal outcomes. NSAIDs (Nonsteroidal Anti-Inflammatory Drugs) are often essential agents
in the management of arthritis, but they also may be commonly employed for conditions which are less serious.
Physicians may wish to discuss with their patients the potential risks and likely benefits of NSAID treatment,
particularly when the drugs are used for less serious conditions where treatment without NSAIDs may represent an
acceptable alternative to both the patient and physician.
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Organisms Affected
Humans and other mammals