Mezlocillin
Mezlocillin Brand names, Mezlocillin Analogs
Mezlocillin Brand Names Mixture
- No information avaliable
Mezlocillin Chemical_Formula
C21H25N5O8S2
Mezlocillin RX_link
No information avaliable
Mezlocillin fda sheet
Mezlocillin msds (material safety sheet)
Mezlocillin Synthesis Reference
No information avaliable
Mezlocillin Molecular Weight
539.584 g/mol
Mezlocillin Melting Point
No information avaliable
Mezlocillin H2O Solubility
No information avaliable
Mezlocillin State
Solid
Mezlocillin LogP
-0.249
Mezlocillin Dosage Forms
Powder for solution (for IV or IM injection)
Mezlocillin Indication
Used to treat serious gram–negative infections of the lungs, urinary tract, and skin.
Mezlocillin Pharmacology
Mezlocillin is a penicillin beta-lactam antibiotic used in the treatment of bacterial infections caused by susceptible, usually gram-positive, organisms. The name "penicillin" can either refer to several variants of penicillin available, or to the group of antibiotics derived from the penicillins. Mezlocillin has in vitro activity against gram-positive and gram-negative aerobic and anaerobic bacteria. The bactericidal activity of mezlocillin results from the inhibition of cell wall synthesis and is mediated through mezlocillin binding to penicillin binding proteins (PBPs). Mezlocillin is stable against hydrolysis by a variety of beta-lactamases, including penicillinases, and cephalosporinases and extended spectrum beta-lactamases. Mezlocillin can be used to treat susceptible strains of H. influenzae, Klebsiella species, Pseudomonas species, Proteus mirabilis, E. coli, Enterobacter species, Streptococcus faecelis, Peptococcus species, Peptostreptococcus species, Bacteriodes species (including B. fragilis), Morganella morganii, Serratia species, N. gonorrhoeae, P. vulgaris, and Providencia rettgeri. This drug is discontinued in the U.S.
Mezlocillin Absorption
No information avaliable
Mezlocillin side effects and Toxicity
Symptoms of overdose include rash, fever, chills, and peeling skin.
Mezlocillin Patient Information
Mezlocillin Organisms Affected
Enteric bacteria and other eubacteria
