Hydroflumethizide en es it fr

Hydroflumethizide Brand names, Hydroflumethizide Analogs

Hydroflumethizide Brand Names Mixture

  • No information avaliable

Hydroflumethizide Chemical_Formula


Hydroflumethizide RX_link


Hydroflumethizide fda sheet

Hydroflumethizide msds (material safety sheet)

Hydroflumethizide Synthesis Reference

No information avaliable

Hydroflumethizide Molecular Weight

331.294 g/mol

Hydroflumethizide Melting Point

272 - 273 oC

Hydroflumethizide H2O Solubility

No information avaliable

Hydroflumethizide State


Hydroflumethizide LogP


Hydroflumethizide Dosage Forms


Hydroflumethizide Indication

Used as adjunctive therapy in edema associated with congestive heart failure, hepatic cirrhosis, and corticosteroid and estrogen therapy. Also used in the management of hypertension either as the sole therapeutic agent or to enhance the effect of other antihypertensive drugs in the more severe forms of hypertension.

Hydroflumethizide Pharmacology

Hydroflumethiazide is an oral thiazide used to treat hypertension and edema. High blood pressure adds to the workload of the heart and arteries. If it continues for a long time, the heart and arteries may not function properly. This can damage the blood vessels of the brain, heart, and kidneys, resulting in a stroke, heart failure, or kidney failure. High blood pressure may also increase the risk of heart attacks. Like other thiazides, Hydroflumethiazide promotes water loss from the body (diuretics). Thiazides inhibit Na+/Cl- reabsorption from the distal convoluted tubules in the kidneys. Thiazides also cause loss of potassium and an increase in serum uric acid. Thiazides are often used to treat hypertension, but their hypotensive effects are not necessarily due to their diuretic activity. Thiazides have been shown to prevent hypertension-related morbidity and mortality although the mechanism is not fully understood. Thiazides cause vasodilation by activating calcium-activated potassium channels (large conductance) in vascular smooth muscles and inhibiting various carbonic anhydrases in vascular tissue.

Hydroflumethizide Absorption

Hydroflumethiazide is incompletely but fairly rapidly absorbed from the gastrointestinal tract

Hydroflumethizide side effects and Toxicity

Overdoses lead to diuresis, lethargy progressing to coma, with minimal cardiorespiratory depression and with or without significant serum electrolyte changes or dehydration.

Hydroflumethizide Patient Information

Hydroflumethizide Organisms Affected

Humans and other mammals