Opiran

Opiran Brand names, Opiran Analogs

Opiran Brand Names Mixture

No information avaliable

Opiran Chemical_Formula

C₂₈H₂₉F₂N₃O

Opiran RX_link

http://www.rxlist.com/cgi/generic3/orap.htm

Opiran fda sheet

Opiran msds (material safety sheet)

Opiran MSDS

Opiran Synthesis Reference

No information avaliable

Opiran Molecular Weight

461.546 g/mol

Opiran Melting Point

214-218 ^oC

Opiran H₂O Solubility

10 mg/L

Opiran State

Solid

Opiran LogP

5.761

Opiran Dosage Forms

Tablet

Opiran Indication

Used for the suppression of motor and phonic tics in patients with Tourette's Disorder who have failed to respond satisfactorily to standard treatment.

Opiran Pharmacology

Pimozide is an orally active antipsychotic drug product which shares with other antipsychotics the ability to blockade dopaminergic receptors on neurons in the central nervous system. However, receptor blockade is often accompanied by a series of secondary alterations in central dopamine metabolism and function which may contribute to both pimozide's therapeutic and untoward effects. In addition, pimozide, in common with other antipsychotic drugs, has various effects on other central nervous system receptor systems which are not fully characterized. Pimozide also has less potential for inducing sedation and hypotension as it has more specific dopamine receptor blocking activity than other neuroleptic agents (and is therefore a suitable alternative to haloperidol).

Opiran Absorption

Greater than 50% absorption after oral administration. Serum peak appears 6-8 hours post ingestion.

Opiran side effects and Toxicity

LD₅₀ = 1100 mg/kg (rat, oral), 228 mg/kg (mouse, oral)

Opiran Patient Information