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Guanethidine Brand names, Guanethidine Analogs

Guanethidine Brand Names Mixture

  • No information avaliable

Guanethidine Chemical_Formula


Guanethidine RX_link

No information avaliable

Guanethidine fda sheet

Guanethidine msds (material safety sheet)

Guanethidine MSDS

Guanethidine Synthesis Reference

No information avaliable

Guanethidine Molecular Weight

198.309 g/mol

Guanethidine Melting Point

250 oC (sulfate salt)

Guanethidine H2O Solubility

Very soluble

Guanethidine State


Guanethidine LogP


Guanethidine Dosage Forms


Guanethidine Indication

For the treatment of moderate and severe hypertension, either alone or as an adjunct, and for the treatment of renal hypertension.

Guanethidine Pharmacology

High blood pressure can cause the heart and arteries to not function properly. This can damage the blood vessels of the brain, heart, and kidneys, resulting in a stroke, heart failure, or kidney failure. High blood pressure may also increase the risk of heart attacks. These problems may be less likely to occur if blood pressure is controlled. Guanethidine works by decreasing the heart rate and relaxing the blood vessels so that blood can flow more easily through the body, thereby reducing these risks. It is a postganglionic sympathetic nerve terminal blocker that prevents the release of norepinephrine from nerve terminals.

Guanethidine Absorption

3-30% of oral dose (poor and highly variable)

Guanethidine side effects and Toxicity

Side effects include drowsiness, dizziness, tiredness or confusion. LD50=1000 mg/kg (mouse, oral)

Guanethidine Patient Information

Guanethidine Organisms Affected

Humans and other mammals