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Apo-Guanethidine Brand names, Apo-Guanethidine Analogs

Apo-Guanethidine Brand Names Mixture

  • No information avaliable

Apo-Guanethidine Chemical_Formula


Apo-Guanethidine RX_link

No information avaliable

Apo-Guanethidine fda sheet

Apo-Guanethidine msds (material safety sheet)

Apo-Guanethidine MSDS

Apo-Guanethidine Synthesis Reference

No information avaliable

Apo-Guanethidine Molecular Weight

198.309 g/mol

Apo-Guanethidine Melting Point

250 oC (sulfate salt)

Apo-Guanethidine H2O Solubility

Very soluble

Apo-Guanethidine State


Apo-Guanethidine LogP


Apo-Guanethidine Dosage Forms


Apo-Guanethidine Indication

For the treatment of moderate and severe hypertension, either alone or as an adjunct, and for the treatment of renal hypertension.

Apo-Guanethidine Pharmacology

High blood pressure can cause the heart and arteries to not function properly. This can damage the blood vessels of the brain, heart, and kidneys, resulting in a stroke, heart failure, or kidney failure. High blood pressure may also increase the risk of heart attacks. These problems may be less likely to occur if blood pressure is controlled. Guanethidine works by decreasing the heart rate and relaxing the blood vessels so that blood can flow more easily through the body, thereby reducing these risks. It is a postganglionic sympathetic nerve terminal blocker that prevents the release of norepinephrine from nerve terminals.

Apo-Guanethidine Absorption

3-30% of oral dose (poor and highly variable)

Apo-Guanethidine side effects and Toxicity

Side effects include drowsiness, dizziness, tiredness or confusion. LD50=1000 mg/kg (mouse, oral)

Apo-Guanethidine Patient Information


Apo-Guanethidine Organisms Affected

Humans and other mammals