Fosinopril

Fosinopril Brand names, Fosinopril Analogs

Fosinopril Brand Names Mixture

No information avaliable

Fosinopril Chemical_Formula

C₃₀H₄₆NO₇P

Fosinopril RX_link

http://www.rxlist.com/cgi/generic/fosinop.htm

Fosinopril fda sheet

Fosinopril FDA

Fosinopril msds (material safety sheet)

Fosinopril Synthesis Reference

E. W. Petrillo, Jr., U.S. Pat. 4,337,201 (1982)

Fosinopril Molecular Weight

563.663 g/mol

Fosinopril Melting Point

149-153^oC

Fosinopril H₂O Solubility

Insoluble

Fosinopril State

Solid

Fosinopril LogP

6.61

Fosinopril Dosage Forms

Tablet

Fosinopril Indication

For the treatment of hypertension. It may be used alone or in combination with thiazide diuretics. It is alos indicated in the management of heart failure.

Fosinopril Pharmacology

Fosinopril, an angiotensin-converting enzyme (ACE) inhibitor. ACE is a peptidyl dipeptidase that catalyzes the conversion of angiotensin I to the vasoconstrictor substance, angiotensin II. By blocking ACE, Fosinopril decreases angiotensin II which is a vasoconstrictor. Fosinopril is used to treat hypertension and heart failure, to reduce proteinuria and renal disease in patients with nephropathies, and to prevent stroke, myocardial infarction, and cardiac death in high-risk patients. Angiotensin II also stimulates aldosterone secretion by the adrenal cortex.

Fosinopril Absorption

~36% of an oral dose

Fosinopril side effects and Toxicity

No information avaliable

Fosinopril Patient Information