Acecor
Brand names,
Acecor
Analogs
Acecor
Brand Names Mixture
Acecor
Chemical_Formula
C30H46NO7P
Acecor
RX_link
http://www.rxlist.com/cgi/generic/fosinop.htm
Acecor
fda sheet
Acecor
msds (material safety sheet)
Acecor
Synthesis Reference
E. W. Petrillo, Jr., U.S. Pat. 4,337,201 (1982)
Acecor
Molecular Weight
563.663 g/mol
Acecor
Melting Point
149-153oC
Acecor
H2O Solubility
Insoluble
Acecor
State
Solid
Acecor
LogP
6.61
Acecor
Dosage Forms
Tablet
Acecor
Indication
For the treatment of hypertension. It may be used alone or in combination with thiazide diuretics. It is alos indicated in the management of heart failure.
Acecor
Pharmacology
Fosinopril, an angiotensin-converting enzyme (ACE) inhibitor. ACE is a peptidyl dipeptidase that catalyzes the conversion of angiotensin I to the vasoconstrictor substance, angiotensin II. By blocking ACE, Fosinopril decreases angiotensin II which is a vasoconstrictor. Fosinopril is used to treat hypertension and heart failure, to reduce proteinuria and renal disease in patients with nephropathies, and to prevent stroke, myocardial infarction, and cardiac death in high-risk patients. Angiotensin II also stimulates aldosterone secretion by the adrenal cortex.
Acecor
Absorption
~36% of an oral dose
Acecor
side effects and Toxicity
No information avaliable
Acecor
Patient Information
No information avaliable
Acecor
Organisms Affected
Humans and other mammals