Fosinopril Sodium

Fosinopril Sodium Brand names, Fosinopril Sodium Analogs

Fosinopril Sodium Brand Names Mixture

No information avaliable

Fosinopril Sodium Chemical_Formula

C₃₀H₄₆NO₇P

Fosinopril Sodium RX_link

http://www.rxlist.com/cgi/generic/fosinop.htm

Fosinopril Sodium fda sheet

Fosinopril_Sodium FDA

Fosinopril Sodium msds (material safety sheet)

Fosinopril Sodium Synthesis Reference

E. W. Petrillo, Jr., U.S. Pat. 4,337,201 (1982)

Fosinopril Sodium Molecular Weight

563.663 g/mol

Fosinopril Sodium Melting Point

149-153^oC

Fosinopril Sodium H₂O Solubility

Insoluble

Fosinopril Sodium State

Solid

Fosinopril Sodium LogP

6.61

Fosinopril Sodium Dosage Forms

Tablet

Fosinopril Sodium Indication

For the treatment of hypertension. It may be used alone or in combination with thiazide diuretics. It is alos indicated in the management of heart failure.

Fosinopril Sodium Pharmacology

Fosinopril, an angiotensin-converting enzyme (ACE) inhibitor. ACE is a peptidyl dipeptidase that catalyzes the conversion of angiotensin I to the vasoconstrictor substance, angiotensin II. By blocking ACE, Fosinopril decreases angiotensin II which is a vasoconstrictor. Fosinopril is used to treat hypertension and heart failure, to reduce proteinuria and renal disease in patients with nephropathies, and to prevent stroke, myocardial infarction, and cardiac death in high-risk patients. Angiotensin II also stimulates aldosterone secretion by the adrenal cortex.

Fosinopril Sodium Absorption

~36% of an oral dose

Fosinopril Sodium side effects and Toxicity

No information avaliable

Fosinopril Sodium Patient Information