Monopril

Monopril Brand names, Monopril Analogs

Monopril Brand Names Mixture

No information avaliable

Monopril Chemical_Formula

C₃₀H₄₆NO₇P

Monopril RX_link

http://www.rxlist.com/cgi/generic/fosinop.htm

Monopril fda sheet

Monopril FDA

Monopril msds (material safety sheet)

Monopril Synthesis Reference

E. W. Petrillo, Jr., U.S. Pat. 4,337,201 (1982)

Monopril Molecular Weight

563.663 g/mol

Monopril Melting Point

149-153^oC

Monopril H₂O Solubility

Insoluble

Monopril State

Solid

Monopril LogP

6.61

Monopril Dosage Forms

Tablet

Monopril Indication

For the treatment of hypertension. It may be used alone or in combination with thiazide diuretics. It is alos indicated in the management of heart failure.

Monopril Pharmacology

Fosinopril, an angiotensin-converting enzyme (ACE) inhibitor. ACE is a peptidyl dipeptidase that catalyzes the conversion of angiotensin I to the vasoconstrictor substance, angiotensin II. By blocking ACE, Fosinopril decreases angiotensin II which is a vasoconstrictor. Fosinopril is used to treat hypertension and heart failure, to reduce proteinuria and renal disease in patients with nephropathies, and to prevent stroke, myocardial infarction, and cardiac death in high-risk patients. Angiotensin II also stimulates aldosterone secretion by the adrenal cortex.

Monopril Absorption

~36% of an oral dose

Monopril side effects and Toxicity

No information avaliable

Monopril Patient Information