PharmacyCodes



F3TDR en es it fr

F3TDR Brand names, F3TDR Analogs

F3TDR Brand Names Mixture

  • No information avaliable

F3TDR Chemical_Formula

C41H42N4O8

F3TDR RX_link

http://www.rxlist.com/cgi/generic2/verteporfin.htm

F3TDR fda sheet

F3TDR FDA

F3TDR msds (material safety sheet)

F3TDR Synthesis Reference

No information avaliable

F3TDR Molecular Weight

718.794 g/mol

F3TDR Melting Point

No information avaliable

F3TDR H2O Solubility

No information avaliable

F3TDR State

Solid

F3TDR LogP

3.743

F3TDR Dosage Forms

Powder for solution to be mixed for injection (2mg verteporfin/mL reconstituted verteporfin)

F3TDR Indication

For the treatment of patients with predominantly classic subfoveal choroidal neovascularization due to age-related macular degeneration, pathologic myopia or presumed ocular histoplasmosis.

F3TDR Pharmacology

Verteporfin, otherwise known as benzoporphyrin derivative, is a medication used in conjunction with laser treatment to eliminate the abnormal blood vessels in the eye associated with conditions such as the wet form of macular degeneration. Verteporfin accumulates in these abnormal blood vessels and, when stimulated by nonthermal red light with a wavelength of 693 nm in the presence of oxygen, produces highly reactive short-lived singlet oxygen and other reactive oxygen radicals, resulting in local damage to the endothelium and blockage of the vessels.

F3TDR Absorption

No information avaliable

F3TDR side effects and Toxicity

Overdose of drug and/or light in the treated eye may result in nonperfusion of normal retinal vessels with the possibility of severe decrease in vision that could be permanent. An overdose of drug will also result in the prolongation of the period during which the patient remains photosensitive to bright light.

F3TDR Patient Information

F3TDR Organisms Affected

Humans and other mammals