F3T
F3T Brand names, F3T Analogs
F3T Brand Names Mixture
- No information avaliable
F3T Chemical_Formula
C41H42N4O8
F3T RX_link
http://www.rxlist.com/cgi/generic2/verteporfin.htm
F3T fda sheet
F3T msds (material safety sheet)
F3T Synthesis Reference
No information avaliable
F3T Molecular Weight
718.794 g/mol
F3T Melting Point
No information avaliable
F3T H2O Solubility
No information avaliable
F3T State
Solid
F3T LogP
3.743
F3T Dosage Forms
Powder for solution to be mixed for injection (2mg verteporfin/mL reconstituted verteporfin)
F3T Indication
For the treatment of patients with predominantly classic subfoveal choroidal neovascularization due to age-related macular degeneration, pathologic myopia or presumed ocular histoplasmosis.
F3T Pharmacology
Verteporfin, otherwise known as benzoporphyrin derivative, is a medication used in conjunction with laser treatment to eliminate the abnormal blood vessels in the eye associated with conditions such as the wet form of macular degeneration. Verteporfin accumulates in these abnormal blood vessels and, when stimulated by nonthermal red light with a wavelength of 693 nm in the presence of oxygen, produces highly reactive short-lived singlet oxygen and other reactive oxygen radicals, resulting in local damage to the endothelium and blockage of the vessels.
F3T Absorption
No information avaliable
F3T side effects and Toxicity
Overdose of drug and/or light in the treated eye may result in nonperfusion of normal retinal vessels with the possibility of severe decrease in vision that could be permanent. An overdose of drug will also result in the prolongation of the period during which the patient remains photosensitive to bright light.
F3T Patient Information
F3T Organisms Affected
Humans and other mammals
