Ethacrynic acid en es it fr

Ethacrynic acid Brand names, Ethacrynic acid Analogs

Ethacrynic acid Brand Names Mixture

  • No information avaliable

Ethacrynic acid Chemical_Formula


Ethacrynic acid RX_link

Ethacrynic acid fda sheet

Ethacrynic_acid FDA

Ethacrynic acid msds (material safety sheet)

Ethacrynic_acid MSDS

Ethacrynic acid Synthesis Reference

No information avaliable

Ethacrynic acid Molecular Weight

303.137 g/mol

Ethacrynic acid Melting Point

122.5 oC

Ethacrynic acid H2O Solubility

No information avaliable

Ethacrynic acid State


Ethacrynic acid LogP


Ethacrynic acid Dosage Forms

Tablet (25, 50 mg); Powder for solution

Ethacrynic acid Indication

For the treatment of high blood pressure and edema caused by diseases like congestive heart failure, liver failure, and kidney failure.

Ethacrynic acid Pharmacology

Ethacrynic acid is a monosulfonamyl loop or high ceiling diuretic. Ethacrynic acid acts on the ascending limb of the loop of Henle and on the proximal and distal tubules. Urinary output is usually dose dependent and related to the magnitude of fluid accumulation. Water and electrolyte excretion may be increased several times over that observed with thiazide diuretics, since ethacrynic acid inhibits reabsorption of a much greater proportion of filtered sodium than most other diuretic agents. Therefore, ethacrynic acid is effective in many patients who have significant degrees of renal insufficiency. Ethacrynic acid has little or no effect on glomerular filtration or on renal blood flow, except following pronounced reductions in plasma volume when associated with rapid diuresis.

Ethacrynic acid Absorption

Onset of action is rapid, usually within 30 minutes after an oral dose of ethacrynic acid or within 5 minutes after an intravenous injection of ethacrynic acid.

Ethacrynic acid side effects and Toxicity

Overdosage may lead to excessive diuresis with electrolyte depletion.

Ethacrynic acid Patient Information

No information avaliable

Ethacrynic acid Organisms Affected

Humans and other mammals