Ethacrynate en es it fr

Ethacrynate Brand names, Ethacrynate Analogs

Ethacrynate Brand Names Mixture

  • No information avaliable

Ethacrynate Chemical_Formula


Ethacrynate RX_link

Ethacrynate fda sheet

Ethacrynate FDA

Ethacrynate msds (material safety sheet)

Ethacrynate MSDS

Ethacrynate Synthesis Reference

No information avaliable

Ethacrynate Molecular Weight

303.137 g/mol

Ethacrynate Melting Point

122.5 oC

Ethacrynate H2O Solubility

No information avaliable

Ethacrynate State


Ethacrynate LogP


Ethacrynate Dosage Forms

Tablet (25, 50 mg); Powder for solution

Ethacrynate Indication

For the treatment of high blood pressure and edema caused by diseases like congestive heart failure, liver failure, and kidney failure.

Ethacrynate Pharmacology

Ethacrynic acid is a monosulfonamyl loop or high ceiling diuretic. Ethacrynic acid acts on the ascending limb of the loop of Henle and on the proximal and distal tubules. Urinary output is usually dose dependent and related to the magnitude of fluid accumulation. Water and electrolyte excretion may be increased several times over that observed with thiazide diuretics, since ethacrynic acid inhibits reabsorption of a much greater proportion of filtered sodium than most other diuretic agents. Therefore, ethacrynic acid is effective in many patients who have significant degrees of renal insufficiency. Ethacrynic acid has little or no effect on glomerular filtration or on renal blood flow, except following pronounced reductions in plasma volume when associated with rapid diuresis.

Ethacrynate Absorption

Onset of action is rapid, usually within 30 minutes after an oral dose of ethacrynic acid or within 5 minutes after an intravenous injection of ethacrynic acid.

Ethacrynate side effects and Toxicity

Overdosage may lead to excessive diuresis with electrolyte depletion.

Ethacrynate Patient Information

No information avaliable

Ethacrynate Organisms Affected

Humans and other mammals