Etacrinic acid en es it fr

Etacrinic acid Brand names, Etacrinic acid Analogs

Etacrinic acid Brand Names Mixture

  • No information avaliable

Etacrinic acid Chemical_Formula


Etacrinic acid RX_link

Etacrinic acid fda sheet

Etacrinic_acid FDA

Etacrinic acid msds (material safety sheet)

Etacrinic_acid MSDS

Etacrinic acid Synthesis Reference

No information avaliable

Etacrinic acid Molecular Weight

303.137 g/mol

Etacrinic acid Melting Point

122.5 oC

Etacrinic acid H2O Solubility

No information avaliable

Etacrinic acid State


Etacrinic acid LogP


Etacrinic acid Dosage Forms

Tablet (25, 50 mg); Powder for solution

Etacrinic acid Indication

For the treatment of high blood pressure and edema caused by diseases like congestive heart failure, liver failure, and kidney failure.

Etacrinic acid Pharmacology

Ethacrynic acid is a monosulfonamyl loop or high ceiling diuretic. Ethacrynic acid acts on the ascending limb of the loop of Henle and on the proximal and distal tubules. Urinary output is usually dose dependent and related to the magnitude of fluid accumulation. Water and electrolyte excretion may be increased several times over that observed with thiazide diuretics, since ethacrynic acid inhibits reabsorption of a much greater proportion of filtered sodium than most other diuretic agents. Therefore, ethacrynic acid is effective in many patients who have significant degrees of renal insufficiency. Ethacrynic acid has little or no effect on glomerular filtration or on renal blood flow, except following pronounced reductions in plasma volume when associated with rapid diuresis.

Etacrinic acid Absorption

Onset of action is rapid, usually within 30 minutes after an oral dose of ethacrynic acid or within 5 minutes after an intravenous injection of ethacrynic acid.

Etacrinic acid side effects and Toxicity

Overdosage may lead to excessive diuresis with electrolyte depletion.

Etacrinic acid Patient Information

No information avaliable

Etacrinic acid Organisms Affected

Humans and other mammals