Etakrinic acid en es it fr

Etakrinic acid Brand names, Etakrinic acid Analogs

Etakrinic acid Brand Names Mixture

  • No information avaliable

Etakrinic acid Chemical_Formula


Etakrinic acid RX_link

Etakrinic acid fda sheet

Etakrinic_acid FDA

Etakrinic acid msds (material safety sheet)

Etakrinic_acid MSDS

Etakrinic acid Synthesis Reference

No information avaliable

Etakrinic acid Molecular Weight

303.137 g/mol

Etakrinic acid Melting Point

122.5 oC

Etakrinic acid H2O Solubility

No information avaliable

Etakrinic acid State


Etakrinic acid LogP


Etakrinic acid Dosage Forms

Tablet (25, 50 mg); Powder for solution

Etakrinic acid Indication

For the treatment of high blood pressure and edema caused by diseases like congestive heart failure, liver failure, and kidney failure.

Etakrinic acid Pharmacology

Ethacrynic acid is a monosulfonamyl loop or high ceiling diuretic. Ethacrynic acid acts on the ascending limb of the loop of Henle and on the proximal and distal tubules. Urinary output is usually dose dependent and related to the magnitude of fluid accumulation. Water and electrolyte excretion may be increased several times over that observed with thiazide diuretics, since ethacrynic acid inhibits reabsorption of a much greater proportion of filtered sodium than most other diuretic agents. Therefore, ethacrynic acid is effective in many patients who have significant degrees of renal insufficiency. Ethacrynic acid has little or no effect on glomerular filtration or on renal blood flow, except following pronounced reductions in plasma volume when associated with rapid diuresis.

Etakrinic acid Absorption

Onset of action is rapid, usually within 30 minutes after an oral dose of ethacrynic acid or within 5 minutes after an intravenous injection of ethacrynic acid.

Etakrinic acid side effects and Toxicity

Overdosage may lead to excessive diuresis with electrolyte depletion.

Etakrinic acid Patient Information

No information avaliable

Etakrinic acid Organisms Affected

Humans and other mammals