Droperidol en es it fr

Droperidol Brand names, Droperidol Analogs

Droperidol Brand Names Mixture

  • No information avaliable

Droperidol Chemical_Formula


Droperidol RX_link


Droperidol fda sheet

Droperidol msds (material safety sheet)

Droperidol MSDS

Droperidol Synthesis Reference

No information avaliable

Droperidol Molecular Weight

379.428 g/mol

Droperidol Melting Point

145.75 oC

Droperidol H2O Solubility

4.21 mg/L

Droperidol State


Droperidol LogP


Droperidol Dosage Forms

Liquid; Solution

Droperidol Indication

Used to produce tranquilization and to reduce the incidence of nausea and vomiting in surgical and diagnostic procedures.

Droperidol Pharmacology

Droperidol produces marked tranquilization and sedation. It allays apprehension and provides a state of mental detachment and indifference while maintaining a state of reflex alertness. Droperidol produces an antiemetic effect as evidenced by the antagonism of apomorphine in dogs. It lowers the incidence of nausea and vomiting during surgical procedures and provides antiemetic protection in the postoperative period. Droperidol potentiates other CNS depressants. It produces mild alpha-adrenergic blockade, peripheral vascular dilatation and reduction of the pressor effect of epinephrine. It can produce hypotension and decreased peripheral vascular resistance and may decrease pulmonary arterial pressure (particularly if it is abnormally high). It may reduce the incidence of epinephrine-induced arrhythmias, but it does not prevent other cardiac arrhythmias.

Droperidol Absorption

Completely absorbed following intramuscular administration.

Droperidol side effects and Toxicity

The intravenous LD50 of droperidol is 20-43 mg/kg in mice; 30 mg/kg in rats; 25 mg/kg in dogs and 11-13 mg/kg in rabbits. The intramuscular LD50 of droperidol is 195 mg/kg in mice, 104-110 mg/kg in rats; 97 mg/kg in rabbits and 200 mg/kg in guinea pigs. The manifestations of droperidol overdosage are an extension of its pharmacologic actions.

Droperidol Patient Information

Droperidol Organisms Affected

Humans and other mammals