Diflorasone
Diflorasone Brand names, Diflorasone Analogs
Diflorasone Brand Names Mixture
- No information avaliable
Diflorasone Chemical_Formula
C26H32F2O7
Diflorasone RX_link
http://www.rxlist.com/cgi/generic/diflorasone.htm
Diflorasone fda sheet
Diflorasone msds (material safety sheet)
Diflorasone Synthesis Reference
No information avaliable
Diflorasone Molecular Weight
494.525 g/mol
Diflorasone Melting Point
No information avaliable
Diflorasone H2O Solubility
No information avaliable
Diflorasone State
Solid
Diflorasone LogP
2.465
Diflorasone Dosage Forms
Cream; Ointment
Diflorasone Indication
For relief of the inflammatory and pruritic manifestations of corticosteroid responsive dermatoses.
Diflorasone Pharmacology
Like other topical corticosteroids, diflorasone has anti-inflammatory, antipruritic, and vasoconstrictive properties. Once absorbed through the skin, topical corticosteroids are handled through pharmacokinetic pathways similar to systemically administered corticosteroids. Diflorasone is a potent topical corticosteroid that should not be used with occlusive dressings. It is recommended that treatment should be limited to 2 consecutive weeks and therapy should be discontinued when adequate results have been achieved.
Diflorasone Absorption
Topical corticosteroids can be absorbed from intact healthy skin. The extent of percutaneous absorption of topical corticosteroids is determined by many factors, including the vehicle and the integrity of the epidermal barrier. Occlusion, inflammation and/or other disease processes in the skin may also increase percutaneous absorption.
Diflorasone side effects and Toxicity
Topically applied diflorasone can be absorbed in sufficient amounts to produce systemic effects. Symptoms of overdose include thinning of skin and suppression of adrenal cortex (decreased ability to respond to stress).
Diflorasone Patient Information
Diflorasone Organisms Affected
Humans and other mammals
