Florone
Florone Brand names, Florone Analogs
Florone Brand Names Mixture
- No information avaliable
Florone Chemical_Formula
C26H32F2O7
Florone RX_link
http://www.rxlist.com/cgi/generic/diflorasone.htm
Florone fda sheet
Florone msds (material safety sheet)
Florone Synthesis Reference
No information avaliable
Florone Molecular Weight
494.525 g/mol
Florone Melting Point
No information avaliable
Florone H2O Solubility
No information avaliable
Florone State
Solid
Florone LogP
2.465
Florone Dosage Forms
Cream; Ointment
Florone Indication
For relief of the inflammatory and pruritic manifestations of corticosteroid responsive dermatoses.
Florone Pharmacology
Like other topical corticosteroids, diflorasone has anti-inflammatory, antipruritic, and vasoconstrictive properties. Once absorbed through the skin, topical corticosteroids are handled through pharmacokinetic pathways similar to systemically administered corticosteroids. Diflorasone is a potent topical corticosteroid that should not be used with occlusive dressings. It is recommended that treatment should be limited to 2 consecutive weeks and therapy should be discontinued when adequate results have been achieved.
Florone Absorption
Topical corticosteroids can be absorbed from intact healthy skin. The extent of percutaneous absorption of topical corticosteroids is determined by many factors, including the vehicle and the integrity of the epidermal barrier. Occlusion, inflammation and/or other disease processes in the skin may also increase percutaneous absorption.
Florone side effects and Toxicity
Topically applied diflorasone can be absorbed in sufficient amounts to produce systemic effects. Symptoms of overdose include thinning of skin and suppression of adrenal cortex (decreased ability to respond to stress).
Florone Patient Information
Florone Organisms Affected
Humans and other mammals
