Cotazym (Organon)
Cotazym (Organon) Brand names, Cotazym (Organon) Analogs
Cotazym (Organon) Brand Names Mixture
- No information avaliable
Cotazym (Organon) Chemical_Formula
C5850H8902N1606O1739S49
Cotazym (Organon) RX_link
http://www.rxlist.com/cgi/generic2/pancrel.htm
Cotazym (Organon) fda sheet
Cotazym (Organon) msds (material safety sheet)
Cotazym (Organon) Synthesis Reference
No information avaliable
Cotazym (Organon) Molecular Weight
131125.6
Cotazym (Organon) Melting Point
48-50 oC (Vinogradov, A.A. et al., Protein Eng. 14:683-689 (2001)).
Cotazym (Organon) H2O Solubility
No information avaliable
Cotazym (Organon) State
Liquid
Cotazym (Organon) LogP
No information avaliable
Cotazym (Organon) Dosage Forms
Tablet
Cotazym (Organon) Indication
For treatment of cystic fibrosis, chronic pancreatitis, pancreatic duct blockage
Cotazym (Organon) Pharmacology
Used in the treatment of cystic fibrosis or pancreatic dysfunction, pancrelipase helps improve fat digestion in the small intestine. Specifically, the lipase, protease and amylase components break down fat, protein, and starches, respectively, in the small intestine. Lipase hydrolyzes fats into glycerol and fatty acids. Protease converts proteins into proteoses and derived substances, while amylase converts starches into dextrins and sugars. Pancreatic enzymes are used to correct maldigestion, malabsorption and pain associated with pancreatic insufficiency. The major maldigestion/malabsorption problems arise from incomplete fat digestion. Exogenous pancrelipase reduces the amount of nitrogen and fat excreted in the stool.
Cotazym (Organon) Absorption
No information avaliable
Cotazym (Organon) side effects and Toxicity
No information avaliable
Cotazym (Organon) Patient Information
No information avaliable
Cotazym (Organon) Organisms Affected
Humans and other mammals
