Pancreatic alpha-amylase precursor
Brand names,
Pancreatic alpha-amylase precursor
Analogs
Pancreatic alpha-amylase precursor
Brand Names Mixture
Pancreatic alpha-amylase precursor
Chemical_Formula
C5850H8902N1606O1739S49
Pancreatic alpha-amylase precursor
RX_link
http://www.rxlist.com/cgi/generic2/pancrel.htm
Pancreatic alpha-amylase precursor
fda sheet
Pancreatic alpha-amylase precursor
msds (material safety sheet)
Pancreatic alpha-amylase precursor
Synthesis Reference
No information avaliable
Pancreatic alpha-amylase precursor
Molecular Weight
131125.6
Pancreatic alpha-amylase precursor
Melting Point
48-50 oC (Vinogradov, A.A. et al., Protein Eng. 14:683-689 (2001)).
Pancreatic alpha-amylase precursor
H2O Solubility
No information avaliable
Pancreatic alpha-amylase precursor
State
Liquid
Pancreatic alpha-amylase precursor
LogP
No information avaliable
Pancreatic alpha-amylase precursor
Dosage Forms
Tablet
Pancreatic alpha-amylase precursor
Indication
For treatment of cystic fibrosis, chronic pancreatitis, pancreatic duct blockage
Pancreatic alpha-amylase precursor
Pharmacology
Used in the treatment of cystic fibrosis or pancreatic dysfunction, pancrelipase helps improve fat digestion in the small intestine. Specifically, the lipase, protease and amylase components break down fat, protein, and starches, respectively, in the small intestine. Lipase hydrolyzes fats into glycerol and fatty acids. Protease converts proteins into proteoses and derived substances, while amylase converts starches into dextrins and sugars. Pancreatic enzymes are used to correct maldigestion, malabsorption and pain associated with pancreatic insufficiency. The major maldigestion/malabsorption problems arise from incomplete fat digestion. Exogenous pancrelipase reduces the amount of nitrogen and fat excreted in the stool.
Pancreatic alpha-amylase precursor
Absorption
No information avaliable
Pancreatic alpha-amylase precursor
side effects and Toxicity
No information avaliable
Pancreatic alpha-amylase precursor
Patient Information
No information avaliable
Pancreatic alpha-amylase precursor
Organisms Affected
Humans and other mammals