Pancrease (Ortho-McNeil)
Pancrease (Ortho-McNeil) Brand names, Pancrease (Ortho-McNeil) Analogs
Pancrease (Ortho-McNeil) Brand Names Mixture
- No information avaliable
Pancrease (Ortho-McNeil) Chemical_Formula
C5850H8902N1606O1739S49
Pancrease (Ortho-McNeil) RX_link
http://www.rxlist.com/cgi/generic2/pancrel.htm
Pancrease (Ortho-McNeil) fda sheet
Pancrease (Ortho-McNeil) msds (material safety sheet)
Pancrease (Ortho-McNeil) Synthesis Reference
No information avaliable
Pancrease (Ortho-McNeil) Molecular Weight
131125.6
Pancrease (Ortho-McNeil) Melting Point
48-50 oC (Vinogradov, A.A. et al., Protein Eng. 14:683-689 (2001)).
Pancrease (Ortho-McNeil) H2O Solubility
No information avaliable
Pancrease (Ortho-McNeil) State
Liquid
Pancrease (Ortho-McNeil) LogP
No information avaliable
Pancrease (Ortho-McNeil) Dosage Forms
Tablet
Pancrease (Ortho-McNeil) Indication
For treatment of cystic fibrosis, chronic pancreatitis, pancreatic duct blockage
Pancrease (Ortho-McNeil) Pharmacology
Used in the treatment of cystic fibrosis or pancreatic dysfunction, pancrelipase helps improve fat digestion in the small intestine. Specifically, the lipase, protease and amylase components break down fat, protein, and starches, respectively, in the small intestine. Lipase hydrolyzes fats into glycerol and fatty acids. Protease converts proteins into proteoses and derived substances, while amylase converts starches into dextrins and sugars. Pancreatic enzymes are used to correct maldigestion, malabsorption and pain associated with pancreatic insufficiency. The major maldigestion/malabsorption problems arise from incomplete fat digestion. Exogenous pancrelipase reduces the amount of nitrogen and fat excreted in the stool.
Pancrease (Ortho-McNeil) Absorption
No information avaliable
Pancrease (Ortho-McNeil) side effects and Toxicity
No information avaliable
Pancrease (Ortho-McNeil) Patient Information
No information avaliable
Pancrease (Ortho-McNeil) Organisms Affected
Humans and other mammals
