Colistin sodium methanesulfonate from bacillus colistinus en es it fr

Colistin sodium methanesulfonate from bacillus colistinus Brand names, Colistin sodium methanesulfonate from bacillus colistinus Analogs

Colistin sodium methanesulfonate from bacillus colistinus Brand Names Mixture

  • No information avaliable

Colistin sodium methanesulfonate from bacillus colistinus Chemical_Formula

C32H52Br2N4O4

Colistin sodium methanesulfonate from bacillus colistinus RX_link

http://www.rxlist.com/cgi/generic2/demecarium.htm

Colistin sodium methanesulfonate from bacillus colistinus fda sheet

Colistin sodium methanesulfonate from bacillus colistinus msds (material safety sheet)

Colistin sodium methanesulfonate from bacillus colistinus Synthesis Reference

No information avaliable

Colistin sodium methanesulfonate from bacillus colistinus Molecular Weight

716.588 g/mol

Colistin sodium methanesulfonate from bacillus colistinus Melting Point

No information avaliable

Colistin sodium methanesulfonate from bacillus colistinus H2O Solubility

No information avaliable

Colistin sodium methanesulfonate from bacillus colistinus State

Solid

Colistin sodium methanesulfonate from bacillus colistinus LogP

-1.75

Colistin sodium methanesulfonate from bacillus colistinus Dosage Forms

Solution (drops - 0.125% and 0.25%)

Colistin sodium methanesulfonate from bacillus colistinus Indication

For the topical treatment of chronic open-angle glaucoma.

Colistin sodium methanesulfonate from bacillus colistinus Pharmacology

Demecarium is a long-acting cholinesterase inhibitor and potent miotic. Because of its toxicity, it should be reserved for use in patients with open-angle glaucoma or other chronic glaucomas not satisfactorily controlled with the short-acting miotics and other agents. Application of demecarium to the eye produces intense miosis and ciliary muscle contraction due to inhibition of cholinesterase, allowing acetylcholine to accumulate at sites of cholinergic transmission. These effects are accompanied by increased capillary permeability of the ciliary body and iris, increased permeability of the blood-aqueous barrier, and vasodilation. Myopia may be induced or, if present, may be augmented by the increased refractive power of the lens that results from the accommodative effect of the drug.

Colistin sodium methanesulfonate from bacillus colistinus Absorption

No information avaliable

Colistin sodium methanesulfonate from bacillus colistinus side effects and Toxicity

The oral LD50 is 2.96 mg/kg in the mouse. Symptoms of overdose include nausea, vomiting, abdominal cramps, diarrhea, urinary incontinence, salivation, sweating, difficulty in breathing, bradycardia, or cardiac irregularities.

Colistin sodium methanesulfonate from bacillus colistinus Patient Information

No information avaliable

Colistin sodium methanesulfonate from bacillus colistinus Organisms Affected

Humans and other mammals