Ceredase (Genzyme)
Ceredase (Genzyme) Brand names, Ceredase (Genzyme) Analogs
Ceredase (Genzyme) Brand Names Mixture
- No information avaliable
Ceredase (Genzyme) Chemical_Formula
C2532H3854N672O711S16
Ceredase (Genzyme) RX_link
http://www.rxlist.com/cgi/generic2/imiglucerase.htm
Ceredase (Genzyme) fda sheet
Ceredase (Genzyme) msds (material safety sheet)
Ceredase (Genzyme) Synthesis Reference
No information avaliable
Ceredase (Genzyme) Molecular Weight
55597.4
Ceredase (Genzyme) Melting Point
No information avaliable
Ceredase (Genzyme) H2O Solubility
No information avaliable
Ceredase (Genzyme) State
Liquid
Ceredase (Genzyme) LogP
-0.168
Ceredase (Genzyme) Dosage Forms
Powder for solution; Solution (IV injection)
Ceredase (Genzyme) Indication
For the treatment of Gaucher's disease (deficiency in glucocerebrosidase)
Ceredase (Genzyme) Pharmacology
Gaucher disease is characterized by a functional deficiency in Beta-glucocerebrosidase enzymatic activity and the resultant accumulation of lipid glucocerebroside in tissue macrophages which become engorged and are termed Gaucher cells. Gaucher cells are typically found in liver, spleen and bone marrow. This can lead to an enlarged spleen and liver (hepatosplenomegaly). Secondary hematologic sequelae include severe anemia and thrombocytopenia. Injections of imiglucerase into Gaucher disease patients leads to elevated serum levels of the enzyme and reduction in the accumulation of glucocerebroside leading to reduced anemia and thrombocytopenia, reduced spleen and liver size, and decreased cachexia
Ceredase (Genzyme) Absorption
No information avaliable
Ceredase (Genzyme) side effects and Toxicity
No information avaliable
Ceredase (Genzyme) Patient Information
No information avaliable
Ceredase (Genzyme) Organisms Affected
Humans and other mammals
