Cefradroxil
Brand names,
Cefradroxil
Analogs
Cefradroxil
Brand Names Mixture
Cefradroxil
Chemical_Formula
C16H17N3O5S
Cefradroxil
RX_link
http://www.rxlist.com/cgi/generic/cefadrox.htm
Cefradroxil
fda sheet
Cefradroxil
msds (material safety sheet)
Cefradroxil
Synthesis Reference
L. B. Crast, Jr., U.S. Pat. 3,489,752 (1969)
Cefradroxil
Molecular Weight
363.389 g/mol
Cefradroxil
Melting Point
197oC
Cefradroxil
H2O Solubility
1110 mg/L
Cefradroxil
State
Solid
Cefradroxil
LogP
-0.355
Cefradroxil
Dosage Forms
Capsule; Tablet; Oral liquid
Cefradroxil
Indication
For the treatment of the following infections (skin, UTI, ENT) caused by; S. pneumoniae, H. influenzae, staphylococci, S. pyogenes (group A beta-hemolytic streptococci), E. coli, P. mirabilis, Klebsiella sp, coagulase-negative staphylococci and Streptococcus pyogenes
Cefradroxil
Pharmacology
Cefadroxil, a first-generation cephalosporin antibiotic, is used to treat urinary tract infections, skin and skin structure infections, pharyngitis, and tonsillitis.
Cefradroxil
Absorption
Cefadroxil is well absorbed on oral administration; food does not interfere with its absorption.
Cefradroxil
side effects and Toxicity
Nausea, vomiting, diarrhoea, allergic rashes may occur
Cefradroxil
Patient Information
Patients should be counseled that intibacterial drugs including DURICEF should only be used to treat bacterial
infections. They do not treat viral infections (eg. the common cold). When DURICEF is prescribed to treat a bacterial
infection, patients should be told that although it is common to feel better early in the course of therapy, the
medication should be taken exactly as directed. Skipping doses or not completing the full course of therapy may (1)
decrease the effectiveness of the immediate treatment and (2) increase the likelyhood that bacteria will develop
resistance and will not be treatable by DURICEF or other antibacterial drugs in the future.
Cefradroxil
Organisms Affected
Enteric bacteria and other eubacteria