Cefadroxil Monohydrate
Brand names,
Cefadroxil Monohydrate
Analogs
Cefadroxil Monohydrate
Brand Names Mixture
Cefadroxil Monohydrate
Chemical_Formula
C16H17N3O5S
Cefadroxil Monohydrate
RX_link
http://www.rxlist.com/cgi/generic/cefadrox.htm
Cefadroxil Monohydrate
fda sheet
Cefadroxil Monohydrate
msds (material safety sheet)
Cefadroxil Monohydrate
Synthesis Reference
L. B. Crast, Jr., U.S. Pat. 3,489,752 (1969)
Cefadroxil Monohydrate
Molecular Weight
363.389 g/mol
Cefadroxil Monohydrate
Melting Point
197oC
Cefadroxil Monohydrate
H2O Solubility
1110 mg/L
Cefadroxil Monohydrate
State
Solid
Cefadroxil Monohydrate
LogP
-0.355
Cefadroxil Monohydrate
Dosage Forms
Capsule; Tablet; Oral liquid
Cefadroxil Monohydrate
Indication
For the treatment of the following infections (skin, UTI, ENT) caused by; S. pneumoniae, H. influenzae, staphylococci, S. pyogenes (group A beta-hemolytic streptococci), E. coli, P. mirabilis, Klebsiella sp, coagulase-negative staphylococci and Streptococcus pyogenes
Cefadroxil Monohydrate
Pharmacology
Cefadroxil, a first-generation cephalosporin antibiotic, is used to treat urinary tract infections, skin and skin structure infections, pharyngitis, and tonsillitis.
Cefadroxil Monohydrate
Absorption
Cefadroxil is well absorbed on oral administration; food does not interfere with its absorption.
Cefadroxil Monohydrate
side effects and Toxicity
Nausea, vomiting, diarrhoea, allergic rashes may occur
Cefadroxil Monohydrate
Patient Information
Patients should be counseled that intibacterial drugs including DURICEF should only be used to treat bacterial
infections. They do not treat viral infections (eg. the common cold). When DURICEF is prescribed to treat a bacterial
infection, patients should be told that although it is common to feel better early in the course of therapy, the
medication should be taken exactly as directed. Skipping doses or not completing the full course of therapy may (1)
decrease the effectiveness of the immediate treatment and (2) increase the likelyhood that bacteria will develop
resistance and will not be treatable by DURICEF or other antibacterial drugs in the future.
Cefadroxil Monohydrate
Organisms Affected
Enteric bacteria and other eubacteria