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Brand names,
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Analogs
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Brand Names Mixture
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Chemical_Formula
C16H17N3O5S
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RX_link
http://www.rxlist.com/cgi/generic/cefadrox.htm
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fda sheet
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msds (material safety sheet)
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Synthesis Reference
L. B. Crast, Jr., U.S. Pat. 3,489,752 (1969)
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Molecular Weight
363.389 g/mol
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Melting Point
197oC
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H2O Solubility
1110 mg/L
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State
Solid
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LogP
-0.355
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Dosage Forms
Capsule; Tablet; Oral liquid
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Indication
For the treatment of the following infections (skin, UTI, ENT) caused by; S. pneumoniae, H. influenzae, staphylococci, S. pyogenes (group A beta-hemolytic streptococci), E. coli, P. mirabilis, Klebsiella sp, coagulase-negative staphylococci and Streptococcus pyogenes
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Pharmacology
Cefadroxil, a first-generation cephalosporin antibiotic, is used to treat urinary tract infections, skin and skin structure infections, pharyngitis, and tonsillitis.
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Absorption
Cefadroxil is well absorbed on oral administration; food does not interfere with its absorption.
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side effects and Toxicity
Nausea, vomiting, diarrhoea, allergic rashes may occur
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Patient Information
Patients should be counseled that intibacterial drugs including DURICEF should only be used to treat bacterial
infections. They do not treat viral infections (eg. the common cold). When DURICEF is prescribed to treat a bacterial
infection, patients should be told that although it is common to feel better early in the course of therapy, the
medication should be taken exactly as directed. Skipping doses or not completing the full course of therapy may (1)
decrease the effectiveness of the immediate treatment and (2) increase the likelyhood that bacteria will develop
resistance and will not be treatable by DURICEF or other antibacterial drugs in the future.
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Organisms Affected
Enteric bacteria and other eubacteria