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Cefixime Brand names, Cefixime Analogs

Cefixime Brand Names Mixture

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Cefixime Chemical_Formula


Cefixime RX_link


Cefixime fda sheet

Cefixime FDA

Cefixime msds (material safety sheet)

Cefixime MSDS

Cefixime Synthesis Reference

T. Takaya et al., U.S. Pat. 4,409,214 (1981)

Cefixime Molecular Weight

453.452 g/mol

Cefixime Melting Point

218-225 oC

Cefixime H2O Solubility

55.11 mg/L

Cefixime State


Cefixime LogP


Cefixime Dosage Forms

Oral suspension (100 mg/5 mL); Tablet (200 mg and 400 mg); Powder for solution; Powder for suspension

Cefixime Indication

For use in the treatment of the following infections when caused by susceptible strains of the designated microorganisms: (1) uncomplicated urinary tract infections caused by Escherichia coli and Proteus mirabilis, (2) otitis media caused by Haemophilus influenzae (beta-lactamase positive and negative strains), Moraxella catarrhalis (most of which are beta-lactamase positive), and S. pyogenes, (3) pharyngitis and tonsillitis caused by S. pyogenes, (4) acute bronchitis and acute exacerbations of chronic bronchitis caused by Streptococcus pneumoniae and Haemophilus influenzae (beta-lactamase positive and negative strains), and (5) uncomplicated gonorrhea (cervical/urethral) caused by Neisseria gonorrhoeae (penicillinase- and non-penicillinase-producing strains).

Cefixime Pharmacology

Cefixime, an antibiotic, is a third-generation cephalosporin like ceftriaxone and cefotaxime. Cefixime is highly stable in the presence of beta-lactamase enzymes. As a result, many organisms resistant to penicillins and some cephalosporins due to the presence of beta-lactamases, may be susceptible to cefixime. The antibacterial effect of cefixime results from inhibition of mucopeptide synthesis in the bacterial cell wall.

Cefixime Absorption

About 40%-50% absorbed orally whether administered with or without food, however, time to maximal absorption is increased approximately 0.8 hours when administered with food.

Cefixime side effects and Toxicity

Symptoms of overdose include blood in the urine, diarrhea, nausea, upper abdominal pain, and vomiting.

Cefixime Patient Information

Cefixime Organisms Affected

Enteric bacteria and other eubacteria