PharmacyCodes



Carbenicillinfree base en es it fr

Carbenicillinfree base Brand names, Carbenicillinfree base Analogs

Carbenicillinfree base Brand Names Mixture

  • No information avaliable

Carbenicillinfree base Chemical_Formula

C17H18N2O6S

Carbenicillinfree base RX_link

http://www.rxlist.com/cgi/generic3/geocillin.htm

Carbenicillinfree base fda sheet

Carbenicillinfree base msds (material safety sheet)

Carbenicillinfree_base MSDS

Carbenicillinfree base Synthesis Reference

No information avaliable

Carbenicillinfree base Molecular Weight

378.401 g/mol

Carbenicillinfree base Melting Point

No information avaliable

Carbenicillinfree base H2O Solubility

451 mg/L

Carbenicillinfree base State

Solid

Carbenicillinfree base LogP

1.216

Carbenicillinfree base Dosage Forms

Tablets containing 382 mg carbenicillin (for oral use)

Carbenicillinfree base Indication

For the treatment of acute and chronic infections of the upper and lower urinary tract and in asymptomatic bacteriuria due to susceptible strains of bacteria.

Carbenicillinfree base Pharmacology

Carbenicillin is a semisynthetic penicillin. Though carbenicillin provides substantial in vitro activity against a variety of both gram-positive and gram-negative microorganisms, the most important aspect of its profile is in its antipseudomonal and antiproteal activity. Because of the high urine levels obtained following administration, carbenicillin has demonstrated clinical efficacy in urinary infections due to susceptible strains of: Escherichia coli, Proteus mirabilis, Proteus vulgaris, Morganella morganii, Pseudomonas species, Providencia rettgeri, Enterobacter species, and Enterococci (S. faecalis).

Carbenicillinfree base Absorption

Acid stable, and rapidly absorbed from the small intestine following oral administration.

Carbenicillinfree base side effects and Toxicity

Carbenicillin blood levels achievable are very low, and toxic reactions as a function of overdosage should not occur systematically. The oral LD50 in mice is 3,600 mg/kg, in rats 2,000 mg/kg, and in dogs is in excess of 500 mg/kg. The lethal human dose is not known. Symptoms of overdose include diarrhea, nausea, stomach upset, and vomiting.

Carbenicillinfree base Patient Information

No information avaliable

Carbenicillinfree base Organisms Affected

Enteric bacteria and other eubacteria