Atracurium Besylate Preservative Free
Brand names,
Atracurium Besylate Preservative Free
Analogs
Atracurium Besylate Preservative Free
Brand Names Mixture
Atracurium Besylate Preservative Free
Chemical_Formula
C53H72N2O12+2
Atracurium Besylate Preservative Free
RX_link
http://www.rxlist.com/cgi/generic2/trac.htm
Atracurium Besylate Preservative Free
fda sheet
Atracurium Besylate Preservative Free
msds (material safety sheet)
Atracurium Besylate Preservative Free
Synthesis Reference
No information avaliable
Atracurium Besylate Preservative Free
Molecular Weight
929.145 g/mol
Atracurium Besylate Preservative Free
Melting Point
185-194 oC
Atracurium Besylate Preservative Free
H2O Solubility
Miscible
Atracurium Besylate Preservative Free
State
Solid
Atracurium Besylate Preservative Free
LogP
No information avaliable
Atracurium Besylate Preservative Free
Dosage Forms
Injection (10mg/mL)
Atracurium Besylate Preservative Free
Indication
For use, as an adjunct to general anesthesia, to facilitate endotracheal intubation and to provide skeletal muscle relaxation during surgery or mechanical ventilation.
Atracurium Besylate Preservative Free
Pharmacology
Atracurium is a nondepolarizing skeletal muscle relaxant. Atracurium can be used most advantageously if muscle twitch response to peripheral nerve stimulation is monitored to assess degree of muscle relaxation. The duration of neuromuscular block produced by Atracurium is approximately one third to one half the duration of block by d-tubocurarine, metocurine, and pancuronium at initially equipotent doses. As with other nondepolarizing neuromuscular blockers, the time to onset of paralysis decreases and the duration of maximum effect increases with increasing doses of Atracurium. Repeated administration of maintenance doses of Atracurium has no cumulative effect on the duration of neuromuscular block if recovery is allowed to begin prior to repeat dosing. Moreover, the time needed to recover from repeat doses does not change with additional doses. Repeat doses can therefore be administered at relatively regular intervals with predictable results.
Atracurium Besylate Preservative Free
Absorption
No information avaliable
Atracurium Besylate Preservative Free
side effects and Toxicity
Excessive doses can be expected to produce enhanced pharmacological effects. Overdosage may increase the risk of histamine release and cardiovascular effects, especially hypotension.
Atracurium Besylate Preservative Free
Patient Information
Atracurium Besylate Preservative Free
Organisms Affected
Humans and other mammals