Nimbex
Nimbex Brand names, Nimbex Analogs
Nimbex Brand Names Mixture
- No information avaliable
Nimbex Chemical_Formula
C53H72N2O12+2
Nimbex RX_link
http://www.rxlist.com/cgi/generic2/trac.htm
Nimbex fda sheet
Nimbex msds (material safety sheet)
Nimbex Synthesis Reference
No information avaliable
Nimbex Molecular Weight
929.145 g/mol
Nimbex Melting Point
185-194 oC
Nimbex H2O Solubility
Miscible
Nimbex State
Solid
Nimbex LogP
No information avaliable
Nimbex Dosage Forms
Injection (10mg/mL)
Nimbex Indication
For use, as an adjunct to general anesthesia, to facilitate endotracheal intubation and to provide skeletal muscle relaxation during surgery or mechanical ventilation.
Nimbex Pharmacology
Atracurium is a nondepolarizing skeletal muscle relaxant. Atracurium can be used most advantageously if muscle twitch response to peripheral nerve stimulation is monitored to assess degree of muscle relaxation. The duration of neuromuscular block produced by Atracurium is approximately one third to one half the duration of block by d-tubocurarine, metocurine, and pancuronium at initially equipotent doses. As with other nondepolarizing neuromuscular blockers, the time to onset of paralysis decreases and the duration of maximum effect increases with increasing doses of Atracurium. Repeated administration of maintenance doses of Atracurium has no cumulative effect on the duration of neuromuscular block if recovery is allowed to begin prior to repeat dosing. Moreover, the time needed to recover from repeat doses does not change with additional doses. Repeat doses can therefore be administered at relatively regular intervals with predictable results.
Nimbex Absorption
No information avaliable
Nimbex side effects and Toxicity
Excessive doses can be expected to produce enhanced pharmacological effects. Overdosage may increase the risk of histamine release and cardiovascular effects, especially hypotension.
Nimbex Patient Information
Nimbex Organisms Affected
Humans and other mammals
