Atracurium Besylate
Atracurium Besylate Brand names, Atracurium Besylate Analogs
Atracurium Besylate Brand Names Mixture
- No information avaliable
Atracurium Besylate Chemical_Formula
C53H72N2O12+2
Atracurium Besylate RX_link
http://www.rxlist.com/cgi/generic2/trac.htm
Atracurium Besylate fda sheet
Atracurium Besylate msds (material safety sheet)
Atracurium Besylate Synthesis Reference
No information avaliable
Atracurium Besylate Molecular Weight
929.145 g/mol
Atracurium Besylate Melting Point
185-194 oC
Atracurium Besylate H2O Solubility
Miscible
Atracurium Besylate State
Solid
Atracurium Besylate LogP
No information avaliable
Atracurium Besylate Dosage Forms
Injection (10mg/mL)
Atracurium Besylate Indication
For use, as an adjunct to general anesthesia, to facilitate endotracheal intubation and to provide skeletal muscle relaxation during surgery or mechanical ventilation.
Atracurium Besylate Pharmacology
Atracurium is a nondepolarizing skeletal muscle relaxant. Atracurium can be used most advantageously if muscle twitch response to peripheral nerve stimulation is monitored to assess degree of muscle relaxation. The duration of neuromuscular block produced by Atracurium is approximately one third to one half the duration of block by d-tubocurarine, metocurine, and pancuronium at initially equipotent doses. As with other nondepolarizing neuromuscular blockers, the time to onset of paralysis decreases and the duration of maximum effect increases with increasing doses of Atracurium. Repeated administration of maintenance doses of Atracurium has no cumulative effect on the duration of neuromuscular block if recovery is allowed to begin prior to repeat dosing. Moreover, the time needed to recover from repeat doses does not change with additional doses. Repeat doses can therefore be administered at relatively regular intervals with predictable results.
Atracurium Besylate Absorption
No information avaliable
Atracurium Besylate side effects and Toxicity
Excessive doses can be expected to produce enhanced pharmacological effects. Overdosage may increase the risk of histamine release and cardiovascular effects, especially hypotension.
Atracurium Besylate Patient Information
Atracurium Besylate Organisms Affected
Humans and other mammals
