Tracrium Preservative Free
Brand names,
Tracrium Preservative Free
Analogs
Tracrium Preservative Free
Brand Names Mixture
Tracrium Preservative Free
Chemical_Formula
C53H72N2O12+2
Tracrium Preservative Free
RX_link
http://www.rxlist.com/cgi/generic2/trac.htm
Tracrium Preservative Free
fda sheet
Tracrium Preservative Free
msds (material safety sheet)
Tracrium Preservative Free
Synthesis Reference
No information avaliable
Tracrium Preservative Free
Molecular Weight
929.145 g/mol
Tracrium Preservative Free
Melting Point
185-194 oC
Tracrium Preservative Free
H2O Solubility
Miscible
Tracrium Preservative Free
State
Solid
Tracrium Preservative Free
LogP
No information avaliable
Tracrium Preservative Free
Dosage Forms
Injection (10mg/mL)
Tracrium Preservative Free
Indication
For use, as an adjunct to general anesthesia, to facilitate endotracheal intubation and to provide skeletal muscle relaxation during surgery or mechanical ventilation.
Tracrium Preservative Free
Pharmacology
Atracurium is a nondepolarizing skeletal muscle relaxant. Atracurium can be used most advantageously if muscle twitch response to peripheral nerve stimulation is monitored to assess degree of muscle relaxation. The duration of neuromuscular block produced by Atracurium is approximately one third to one half the duration of block by d-tubocurarine, metocurine, and pancuronium at initially equipotent doses. As with other nondepolarizing neuromuscular blockers, the time to onset of paralysis decreases and the duration of maximum effect increases with increasing doses of Atracurium. Repeated administration of maintenance doses of Atracurium has no cumulative effect on the duration of neuromuscular block if recovery is allowed to begin prior to repeat dosing. Moreover, the time needed to recover from repeat doses does not change with additional doses. Repeat doses can therefore be administered at relatively regular intervals with predictable results.
Tracrium Preservative Free
Absorption
No information avaliable
Tracrium Preservative Free
side effects and Toxicity
Excessive doses can be expected to produce enhanced pharmacological effects. Overdosage may increase the risk of histamine release and cardiovascular effects, especially hypotension.
Tracrium Preservative Free
Patient Information
Tracrium Preservative Free
Organisms Affected
Humans and other mammals