Aripiprazole
Brand names,
Aripiprazole
Analogs
Aripiprazole
Brand Names Mixture
Aripiprazole
Chemical_Formula
C23H27Cl2N3O2
Aripiprazole
RX_link
http://www.rxlist.com/cgi/generic/abilify.htm
Aripiprazole
fda sheet
Aripiprazole
msds (material safety sheet)
Aripiprazole
Synthesis Reference
No information avaliable
Aripiprazole
Molecular Weight
448.385 g/mol
Aripiprazole
Melting Point
No information avaliable
Aripiprazole
H2O Solubility
No information avaliable
Aripiprazole
State
Solid
Aripiprazole
LogP
4.537
Aripiprazole
Dosage Forms
No information avaliable
Aripiprazole
Indication
For the treatment of schizophrenia
Aripiprazole
Pharmacology
Aripiprazole is a psychotropic agent belonging to the chemical class of benzisoxazole derivatives and is indicated for the treatment of schizophrenia. Aripiprazole is a selective monoaminergic antagonist with high affinity for the serotonin Type 2 (5HT2), dopamine Type 2 (D2), 1 and 2 adrenergic, and H1 histaminergic receptors. Aripiprazole acts as an antagonist at other receptors, but with lower potency. Antagonism at receptors other than dopamine and 5HT2 with similar receptor affinities may explain some of the other therapeutic and side effects of Aripiprazole. Aripiprazole's antagonism of histamine H1 receptors may explain the somnolence observed with this drug. Aripiprazole's antagonism of adrenergic a1 receptors may explain the orthostatic hypotension observed with this drug.
Aripiprazole
Absorption
No information avaliable
Aripiprazole
side effects and Toxicity
No information avaliable
Aripiprazole
Patient Information
Aripiprazole
Organisms Affected
Humans and other mammals