OPC 31
Brand names,
OPC 31
Analogs
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Brand Names Mixture
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Chemical_Formula
C23H27Cl2N3O2
OPC 31
RX_link
http://www.rxlist.com/cgi/generic/abilify.htm
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fda sheet
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msds (material safety sheet)
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Synthesis Reference
No information avaliable
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Molecular Weight
448.385 g/mol
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Melting Point
No information avaliable
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H2O Solubility
No information avaliable
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State
Solid
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LogP
4.537
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Dosage Forms
No information avaliable
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Indication
For the treatment of schizophrenia
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Pharmacology
Aripiprazole is a psychotropic agent belonging to the chemical class of benzisoxazole derivatives and is indicated for the treatment of schizophrenia. Aripiprazole is a selective monoaminergic antagonist with high affinity for the serotonin Type 2 (5HT2), dopamine Type 2 (D2), 1 and 2 adrenergic, and H1 histaminergic receptors. Aripiprazole acts as an antagonist at other receptors, but with lower potency. Antagonism at receptors other than dopamine and 5HT2 with similar receptor affinities may explain some of the other therapeutic and side effects of Aripiprazole. Aripiprazole's antagonism of histamine H1 receptors may explain the somnolence observed with this drug. Aripiprazole's antagonism of adrenergic a1 receptors may explain the orthostatic hypotension observed with this drug.
OPC 31
Absorption
No information avaliable
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side effects and Toxicity
No information avaliable
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Patient Information
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Organisms Affected
Humans and other mammals